| Date | Opponent | Time/
Results | TV | | Thu, Aug 9 | @ Cowboys | L 23-10 | -- | | Mon, Aug 20 | Bears | L 27-24 | -- | | Sat, Aug 25 | Lions | W 37-10 | -- | | Fri, Aug 30 | @ Bengals | L 14-6 | -- |
| | Thu, Sep 6 | Saints | W 41-10 | -- | | Sun, Sep 16 | @ Titans | W 22-20 | WTHI | | Sun, Sep 23 | @ Texans | W 30-24 | WTHI | | Sun, Sep 30 | Broncos | W 38-20 | WTHI | | Sun, Oct 7 | Buccaneers | W 33-14 | -- | | Sun, Oct 14 | Bye | -- | -- | | Mon, Oct 22 | @ Jaguars | W 29-7 | -- | | Sun, Oct 28 | @ Panthers | W 31-7 | WTHI | | Sun, Nov 4 | Patriots | L 24-20 | WTHI | | Sun, Nov 11 | @ Chargers | W 23-21 | -- | | Sun, Nov 18 | Chiefs | W 13-10 | WTHI | | Thu, Nov 22 | @ Falcons | W 31-13 | -- | | Sun, Dec 2 | Jaguars | W 28-25 | WTHI | | Sun, Dec 9 | @ Ravens | W 44-20 | -- | | Sun, Dec 16 | @ Raiders | W 21-14 | WTHI | | Sun, Dec 23 | Texans | W 38-15 | WTHI | | Sun, Dec 30 | Titans | L 16-10 | WTHI | |
Bob & Tom Present Colts Owner with Special Gift
