Nicole Bengiveno/The New York Times John Holloway, 59, in his apartment designed for the frail elderly. He suffers from illnesses more severe than those of his father, 84. | Aging AIDS patients beset by complex health problems By JANE GROSS Drugs have given patients a future, but many wonder at what cost, as longevity brings a constellation of ailments showing up among the first wave of AIDS survivors to reach late middle age. | | Mind The New Year's cocktail: Regret with a dash of bitters By BENEDICT CAREY Ruminating on paths not taken is an emotionally corrosive exercise and the common wisdom about regret appears to be true. In treating muscular dystrophy, an early drug test shows promise By DENISE GRADY In its first test in humans, an experimental drug, called an "antisense" compound, enabled patients to produce an essential muscle protein that is missing in Duchenne's muscular dystrophy, a genetic disease. Well A clutter too deep for mere bins and shelves By TARA PARKER-POPE Disorganization may be a person problem, not a house problem. Books Migration, interrupted: Nature's rhythms at risk By CARL ZIMMER In a new book, David Wilcove urges conservation of species and their ways, still so little understood. A medicine hunter on a remote path to cures By ANDREW DOWNIE Scouring remote regions for plants, oils and extracts can yield cures — and big profits — for pharmaceutical companies and indigenous tribes. The DNA Age Searching for similar diagnosis through DNA By AMY HARMON Parents of children with distinct genetic mutations are seeking out others to form support networks. Finding Alzheimer's before a mind fails By DENISE GRADY Though Alzheimer's disease seems to strike suddenly in old age, scientists think it begins long before symptoms occur. U.S. hospitals chase a nuclear tool to fight cancer By ANDREW POLLACK A push by medical centers to turn nuclear particle accelerators into weapons against cancer reflects the best and worst of America's health system, experts say. Jared Diamond and his critics: A question of blame when societies fall By GEORGE JOHNSON Who or what is to blame when a once-powerful society collapses? On the ground and in the water, tracing a giant wave's path By CLAUDIA DREIFUS Harindra Joseph Fernando studies the human activities that make a natural disaster even more deadly. As Cuba's economy withers, its ecology thrives Discussing the options for breast cancer surgery Synesthesia: A mixing of the senses when the brain reorganizes Widening of health care in U.S. states hits roadblocks Mind: Brought on by darkness, seasonal disorder needs light Scientists weigh stem cells' role as cancer cause Foster care better for I.Q. than orphanage, study finds At 71, physics professor is a Web star Pet ferret hit by an arrow? Here's a book for you Vital Signs: Parents may not notice obesity in children Well: Can a 'fertility diet' get you pregnant? Personal Health: Teenage risks, and how to avoid them Q & A: Weak eyes, strong eyes Astronauts leave space station to check defective mechanisms News Analysis: U.S. reversal under pressure leads to climate deal Cancer expected to claim 7.6 million lives worldwide this year Parasites in fish farms threaten wild salmon, researchers say Evolution throws a helpful curve toward pregnant women Homespun electricity, from the wind Parkinson's raises risk of depression in family Mars yielding some secrets to rovers Personal Health: Mental reserves keep brains agile Accepting Nobel Peace Prize, Gore again gives warning on climate Making a malaria vaccine à la Louis Pasteur Well: A gift that gives right back? The giving itself Basics: An ancient medicine (enjoy in moderation) Re-planning life after a heart attack Onscreen villain makes doctors wince | |  |  |  | |